A British woman born without a womb has given birth to a healthy daughter – making the little packet of joy the first baby in the UK to be born of a belly transplant.
Grace Davidson, 36, was diagnosed as a teenager with Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome-a rare condition marked by absence or underdevelopment of the uterus.
Determined to experience motherhood, Davidson underwent abdominal transplant in 2023, taking the organ from her older sister, Amy Purdie, who no longer needed her.
In February 2023, after passing an 18-hour operation in Oxford, Davidson became the first UK woman to achieve a successful abdominal transplant.
She then passed through IVF to get one of the seven embryos she and her husband, Angus, were frozen before transplantation.
In February 2025, she gave birth to her daughter, Amy Isabel, through the caesarean section at Queen Charlotte and Chelsea Hospital in London.
Baby – called Amy after her thesis – was healthy, weighing 4.5 pounds at birth.
“It was just hard to believe it was true,” Davidson The Times told. “We were given the biggest gift we could have ever asked.”
“The moment we saw it was extraordinary, and both of us just broke down in emotional tears – it’s hard to describe, it was fun,” her husband said.
“The room was so filled with love and joy and all these people who had a given interest in Amy for extraordinary medical and scientific reasons.”
It was the end of a long fertility journey for Davidsons – and the achievement of the coronation for Professor Richard Smith, a consultant gynecological surgeon who established the charity that funded the initial procedure, the Womb transplant.
“I have to say, I got out of the room in Queen Charlotte’s [hospital] With tears flowing my face. It is the fourth of a century – a good part of my career, “Smith told The Times.
“I feel great joy, in fact, unbelievable – 25 years below the line from the beginning of this study, we finally have a baby, Amy Isabel Little.”
Amy’s middle name honors Isabel Quiroga – another abdominal transplant consultant – who said she was “humble” by the decision.
About 1 in 5,000 women worldwide are born without a womb.
Globally, about 50 babies have been born after abdominal transplants since the first successful procedure in Sweden in 2014.
The National Health Service in Britain (NHS) said he was pleased with the birth of this “miracle” baby and expected the medical moment to provide hope for other women who want to conceive.
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